Article
Protease treatment of nuclear extracts distinguishes between class II MHC X1 box DNA-binding proteins in wild-type and class II-deficient B cells.
Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 1993
Hasegawa S L, Riley J L, Sloan J H, Boss J M
Abstract excerpt
The X box region is critical for directing the expression of class II major histocompatibility complex genes in B lymphocytes. Although several class II promoter-specific DNA binding factors have been described, only the X box region factor, RFX, shows a genetic correlation with class II expressi...
Topics
- B-Lymphocytes
- Cell Line
- Cell Nucleus
- DNA-Binding Proteins
- Endopeptidases
- Genes, MHC Class II
- Histocompatibility Antigens Class II
- Humans
- Mutation
- Regulatory Factor X Transcription Factors
- Transcription Factors