Article
Regulatory factor-X binding to mutant HLA-DRA promoter sequences.
Nucleic acids research - 25 Mar 1991
Hasegawa S L, Sloan J H, Reith W, Mach B, Boss J M
Abstract excerpt
The class II genes of the major histocompatibility complex (MHC) encode a family of cell surface glycoproteins that present processed antigen to the T cell receptor. Class II genes are regulated coordinately, responding to both immunologic and developmental signals. Conserved sequence elements 5'...
Topics
- Animals
- Autoradiography
- Base Sequence
- Binding, Competitive
- DNA-Binding Proteins
- Genes, MHC Class II
- HLA-DR Antigens
- Humans
- Mice
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Plasmids
- Promoter Regions, Genetic
- Regulatory Factor X Transcription Factors
- Transcription Factors
- Tumor Cells, Cultured