Article
[Genetic conversion of neurotransmitter phenotype in transgenic mice].
Nihon rinsho. Japanese journal of clinical medicine - 1 Jan 1993
Kobayashi K, Nagatsu T
Abstract excerpt
The mammalian central and sympathetic nervous systems contain three kinds of catecholaminergic neuron (dopamine, norepinephrine and epinephrine neurons). Adrenal medulla also consists of cells producing either norepinephrine or epinephrine as hormones. To switch of catecholamine phenotype in the nervous and endocrine systems, we generated a line of transgenic mice carrying a chimeric gene containing human...
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