Article
Generation of the tamoxifen-inducible DBH-Cre transgenic mouse line DBH-CT.
Genesis (New York, N.Y. : 2000) - 1 Dec 2011
Stubbusch Jutta, Majdazari Afsaneh, Schmidt Mirko, Schütz Günther, Deller Thomas, Rohrer Hermann
Abstract excerpt
We generated transgenic mice bearing a tamoxifen-dependent Cre recombinase expressed under the control of the dopamine-β-hydroxylase promoter. By crossing to the ROSA26 reporter mice we show that tamoxifen-induced Cre recombinase in adult mice specifically activates β-galactosidase expression in differentiated noradrenergic neurons of the central and peripheral nervous system. Tamoxifen application in adult mice...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
