Article
PNMT transgenic mice have an aggressive phenotype.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme - 1 Mar 2005
Sørensen D B, Johnsen P F, Bibby B M, Böttner A, Bornstein S R, Eisenhofer G, Pacak K, Hansen A K
Abstract excerpt
PNMT (phenylethanolamine-N-methyl-transferase) is the enzyme that catalyzes the formation of epinephrine from norepinephrine. In transgenic mice over-expressing PNMT, observations revealed a very high level of aggression compared to their background strain, C57BL/6J. To evaluate the influence of PNMT on aggression and emotionality in this transgenic line, single-sex male and female groups were independently...
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