Article
The Zucker fatty (fa) gene is not a mutation of corticotropin-releasing factor.
The American journal of physiology - 1 Jan 1993
Smoller J W, Truett G E, Hirsch J, Leibel R L
Abstract excerpt
Corticotropin-releasing factor (CRF) appears to regulate several physiological systems that display prominent abnormalities in Zucker fatty (fa/fa) rats, including the hypothalamic-pituitary-adrenal axis, the autonomic nervous system, and feeding behavior. Moreover, central administration of CRF ameliorates the obese phenotype. In light of these observations, the gene for CRF is a plausible candidate for the...
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