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Article

Screening for variability in the ciliary neurotrophic factor (CNTF) gene: no evidence for association with human obesity.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association - 1 Jan 1998

Münzberg H, Tafel J, Büsing B, Hinney A, Ziegler A, Mayer H, Siegfried W, Matthaei S, Greten H, Hebebrand J, Hamann A

Abstract excerpt

Systemic administration of the neurocytokine ciliary neurotrophic factor (CNTF) normalizes the obese phenotype of ob/ob and db/db mice. CNTF exerts its multiple effects through a receptor complex whose sequence, localization in hypothalamic nuclei and mode of signal transduction share remarkable...

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Source

Identifiers

PMID: 9628240
DOI: 10.1055/s-0029-1211960

Genes

CNTF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-9628240-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Screening for variability in the ciliary neurotrophic factor (CNTF) gene: no evidence for association with human obesity.PMID 9628240Read ↗

Association between CNTF Polymorphisms and Adiposity Markers in European Adolescents.Semantic proximity Read ↗

Ciliary neurotrophic factor (CNTF) genotype and body composition.Semantic proximity Read ↗

Null mutation in human ciliary neurotrophic factor gene confers higher body mass index in males.Semantic proximity Read ↗

Sex-specific effects of CNTF, IL6 and UCP2 polymorphisms on weight gain.Semantic proximity Read ↗

Sequence variants in the human cocaine and amphetamine-regulated transcript (CART) gene in subjects with early onset obesity.Semantic proximity Read ↗

Lack of association between brain-derived neurotrophic factor Val66Met polymorphism and body mass index change over time in healthy adults.Semantic proximity Read ↗

A null mutation in the human CNTF gene is not causally related to neurological diseases.Semantic proximity Read ↗

Ciliary neurotrophic factor null allele frequencies in schizophrenia, affective disorders, and Alzheimer's disease.Semantic proximity Read ↗

Mutation screening and identification of a sequence variation in the human ob gene coding region.Semantic proximity Read ↗

C174T polymorphism in the CNTF receptor gene is associated with fat-free mass in men and women.Semantic proximity Read ↗

[Deficiency of human ciliary neurotropic factor (CNTF) is not causally related to amyotrophic lateral sclerosis (ALS)].Semantic proximity Read ↗

Association between a null mutation in the human ciliary neurotrophic factor (CNTF) gene and increased incidence of psychiatric diseases?Semantic proximity Read ↗

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