Article
Monogenic human obesity syndromes.
Recent progress in hormone research - 1 Jan 2004
Farooqi I S, O'Rahilly S
Abstract excerpt
Over the past decade, we have witnessed a major increase in the scale of scientific activity devoted to the study of energy balance and obesity. This explosion of interest has, to a large extent, been driven by the identification of genes responsible for murine obesity syndromes and the novel physiological pathways revealed by those genetic discoveries. We and others recently have identified several single-gene...
Topics
- Energy Metabolism
- Heterozygote
- Humans
- Leptin
- Mutation
- Obesity
- Phenotype
- Pro-Opiomelanocortin
- Proprotein Convertase 1
- Receptor, Melanocortin, Type 4
- Receptors, Cell Surface
- Receptors, Leptin