Article
Allelic variations clustered in the antigen binding sites of HLA-Bw62 molecules.
Immunogenetics - 1 Jan 1993
Choo S Y, Fan L A, Hansen J A
Abstract excerpt
HLA-Bw62 is a serologically defined class I antigen specificity, but we show that it represents a family of five distinct alleles in this study. Five variants of HLA-Bw62 antigens were identified by isoelectric focusing, and sequencing studies revealed that these are a family of closely related a...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Binding Sites
- Cell Line
- DNA
- HLA-B Antigens
- HLA-B15 Antigen
- Humans
- Isoelectric Focusing
- Molecular Sequence Data
- Phenotype
- Protein Structure, Tertiary
- T-Lymphocytes, Cytotoxic
