Article
Allelic variations clustered in the antigen binding sites of HLA-Bw62 molecules.
Immunogenetics - 1 Jan 1993
Choo S Y, Fan L A, Hansen J A
Abstract excerpt
HLA-Bw62 is a serologically defined class I antigen specificity, but we show that it represents a family of five distinct alleles in this study. Five variants of HLA-Bw62 antigens were identified by isoelectric focusing, and sequencing studies revealed that these are a family of closely related alleles differing from one another by one to six amino acid substitutions at eight positions: 63 in the alpha 1 domain...
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