Article
Increased frequency of HLA-Bw62 and Bw35 CREG antigens in HLA-B27 negative ankylosing spondylitis.
Zeitschrift fur Rheumatologie - 1 Jan 2000
Wagener P, Zeidler H, Eckert G, Deicher H
Abstract excerpt
67 patients with ankylosing spondylitis (AS) were tissue-typed for HLA-A, -B and -C antigens. HLA-Bw62 was found in 6 of 13 (46%) HLA-B27 negative patients, compared to 9% in HLA-B27 positive AS (p greater than 0.01) and 10% in healthy blood donors (p greater than 0.001). HLA-Bw62, a split of the previous HLA-B15, belongs to the HLA-Bw35 CREG antigens, 11 of 13 (85%) of HLA-B27 negative patients had an HLA-Bw35...
Topics
- Adult
- Female
- Gene Frequency
- HLA Antigens
- HLA-B Antigens
- HLA-B15 Antigen
- HLA-B27 Antigen
- HLA-B35 Antigen
- Humans
- Male
- Middle Aged
- Phenotype