A new HLA-B44 variant (B44BO [B*4408]) identified by serology.

doi:10.1111/j.1399-0039.1997.tb02830.x

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Article

A new HLA-B44 variant (B44BO [B*4408]) identified by serology.

Tissue antigens - 1 Jul 1997

Darke C, Street J, Fussell H, Thomas M, Guttridge M, Goldberg T E, Arnett K L, Parham P

Abstract excerpt

Using HLA serology, we detected a new variant of HLA-B44- B44BO- in two families. This antigen reacts with B44 antisera and is negative with over one-third of B12 (B44, B45) sera but reacts with 50% antisera with a B62 component, especially if they contain anti-B57. The variant, B*4408, differs f...

Topics

Alleles
Antibodies
Base Sequence
DNA
Genetic Variation
HLA-B Antigens
HLA-B44 Antigen
Humans
Isoelectric Point
Molecular Sequence Data
Polymerase Chain Reaction

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