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Article

Alpha-2 domain polymorphism and HLA class I peptide loading.

Tissue antigens - 1 Nov 1999

Prilliman K R, Crawford D, Hickman H D, Jackson K W, Wang J, Hildebrand W H

Abstract excerpt

Diversity within the class I HLA antigen binding groove is positioned to moderate the presentation of peptide ligands. Polymorphism is widely dispersed about the peptide binding groove, and unravelling the functional significance of a given polymorphism requires comparative analysis of peptides presented by class I subtypes differing at the position(s) in question. Previous studies have demonstrated that not all...

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Identifiers

PMID: 10599884
DOI: 10.1034/j.1399-0039.1999.540502.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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