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Article

Enhanced expression of human ABC-transporter tap is associated with cellular resistance to mitoxantrone.

FEBS letters - 17 Aug 2001

Lage H, Perlitz C, Abele R, Tampé R, Dietel M, Schadendorf D, Sinha P

Abstract excerpt

Multidrug resistance (MDR) phenotypes have been associated with the overexpression of various members of the superfamily of ATP binding cassette (ABC) transporters. Here we demonstrate that a member of the ABC-transporter family, the heterodimer 'transporter associated with antigen processing' (TAP), physiologically involved in major histocompatibility complex class I-restricted antigen presentation, is...

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Share to ATP Binding Cassette Transporter, Subfamily B, Member 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11513878
DOI: 10.1016/s0014-5793(01)02722-3

Genes

TAP1
TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Enhanced expression of human ABC-transporter tap is associated with cellular resistance to mitoxantrone.PMID 11513878Read ↗

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