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Article

Clinical and genetic studies of renal cell carcinomas in a family with a constitutional chromosome 3;8 translocation. Genetics of familial renal carcinoma.

Annals of internal medicine - 15 Jan 1993

Li F P, Decker H J, Zbar B, Stanton V P, Kovacs G, Seizinger B R, Aburatani H, Sandberg A A, Berg S, Hosoe S, Brown R S

Abstract excerpt

OBJECTIVE: To describe the clinical course and genetic studies of renal carcinoma in members of a family with the constitutional chromosome translocation, t(3;8) (p14;q24). DESIGN: A follow-up study that updates our 1979 report of renal carcinoma in 10 of these relatives. SETTING: A cancer center and university hospital. PATIENTS: Members of the family, including five carriers of the 3;8 translocation who were in...

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PMID: 8416305
DOI: 10.7326/0003-4819-118-2-199301150-00005

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