Comprehensive allelotyping of human renal cell carcinomas using microsatellite DNA probes.

doi:10.1073/pnas.92.7.2854

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Article

Comprehensive allelotyping of human renal cell carcinomas using microsatellite DNA probes.

Proceedings of the National Academy of Sciences of the United States of America - 28 Mar 1995

Thrash-Bingham C A, Greenberg R E, Howard S, Bruzel A, Bremer M, Goll A, Salazar H, Freed J J, Tartof K D

Abstract excerpt

The von Hippel-Lindau locus on chromosome 3p is a tumor suppressor gene known to be involved in nonpapillary renal cell carcinoma. A previous loss of heterozygosity (LOH) study aimed at determining the allelotype of kidney tumors has indicated that in addition to 3p, chromosome arms 5q, 6q, 10q, 11q, 17p, and 19p may also harbor tumor suppressor genes. However, cytogenetic studies reveal that chromosomes 3p, 6q,...

Topics

Alleles
Carcinoma, Papillary
Carcinoma, Renal Cell
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human
Chromosomes, Human, Pair 16
Chromosomes, Human, Pair 3
DNA Probes
DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

DNA, Satellite

Genes, Tumor Suppressor

Genetic Markers

Humans

In Situ Hybridization, Fluorescence

Kidney Neoplasms

Lymphocytes

Ploidies

Source

Open in PubMed Open full text

Identifiers

PMID: 7708737
DOI: 10.1073/pnas.92.7.2854
PMCID: PMC42317

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7708737-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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