Article
Familial papillary renal carcinoma: cytogenetic characterization in normal and tumor tissues in two brothers. A case report.
Urologic oncology - 1 Jan 2000
Gallucci Michele, Vico Erika, Sentinelli Steno, Leonardo Costantino, Visca Paulo, Orlandi Giulia, Cianciulli AnnaMaria
Abstract excerpt
BACKGROUND: Renal tumor subtypes are associated with distinct, recurring cytogenetic abnormalities and hereditary cancer syndromes. In papillary renal carcinoma, trisomy 7 and 17 and loss of the Y chromosome are the most common chromosomal defects. CASE PRESENTATION: The present paper analyzes the chromosomes 7, 17, and Y alterations found in familial papillary carcinoma and in the normal tissue of two brothers....
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