Article
Nonhomologous chromatid exchange in hereditary and sporadic renal cell carcinomas.
Proceedings of the National Academy of Sciences of the United States of America - 1 Jan 1991
Kovacs G, Kung H F
Abstract excerpt
For the development of renal cell carcinomas, it has been suggested that a germ-line or somatic mutation occurs on one of the homologous chromosomes 3p, and subsequently the other 3p segment is lost. We have examined the karyotype and/or the allelic combination on chromosomes 3 and 5 by restriction fragment length polymorphism analysis in normal kidney and tumor samples from 28 renal cell carcinomas that...
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