Article
Generating loss-of-function phenotypes of the fushi tarazu gene with a targeted ribozyme in Drosophila.
Nature - 30 Sept 1993
Zhao J J, Pick L
Abstract excerpt
The ability to isolate gene sequences and analyse their expression patterns has generated demand for mutations created to assess their biological functions. In Drosophila melanogaster this can be achieved by traditional mutagenesis, but this is time-consuming, labour-intensive and not always succ...
Topics
- Animals
- Animals, Genetically Modified
- Bacterial Proteins
- Base Sequence
- DNA
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Enzyme Induction
- Fushi Tarazu Transcription Factors
- Homeodomain Proteins
- Insect Hormones
- Larva
- Molecular Sequence Data
- Nervous System
- Phenotype
- RNA, Antisense
- RNA, Catalytic