Homeodomain-independent activity of the fushi tarazu polypeptide in Drosophila embryos.

doi:10.1038/356610a0

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Homeodomain-independent activity of the fushi tarazu polypeptide in Drosophila embryos.

Nature - 16 Apr 1992

Fitzpatrick V D, Percival-Smith A, Ingles C J, Krause H M

Abstract excerpt

The Drosophila segmentation gene fushi tarazu (ftz) encodes a homeodomain-containing protein, ftz, that can act as a DNA-binding activator of transcription. In the developing embryo, ftz is expressed in seven stripes which correspond to the even-numbered parasegments. These parasegments are missing in ftz- embryos. When ftz is expressed throughout blastoderm embryos under the control of a heat-shock promoter, the...

Topics

Amino Acid Sequence
Animals
Cells, Cultured
Chimera
Chloramphenicol O-Acetyltransferase
Chromosome Deletion
DNA-Binding Proteins
Drosophila
Drosophila Proteins
Embryo, Nonmammalian
Fungal Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Fushi Tarazu Transcription Factors

Genes, Homeobox

Homeodomain Proteins

Insect Hormones

Molecular Sequence Data

Phenotype

Plasmids

Source

Open in PubMed

Identifiers

PMID: 1348571
DOI: 10.1038/356610a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1348571-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Homeodomain-independent activity of the fushi tarazu polypeptide in Drosophila embryos.PMID 1348571Read ↗

A sequence-specific DNA-binding protein that activates fushi tarazu segmentation gene expression.Semantic proximity Read ↗

Near-reciprocal phenotypes caused by inactivation or indiscriminate expression of the Drosophila segmentation gene ftz.Semantic proximity Read ↗

Repression of Drosophila pair-rule segmentation genes by ectopic expression of tramtrack.Semantic proximity Read ↗

Genetic characterization of the homeodomain-independent activity of the Drosophila fushi tarazu gene product.Semantic proximity Read ↗

Patterning of the Drosophila embryo by a homeodomain-deleted Ftz polypeptide.Semantic proximity Read ↗

Low-level ectopic expression of Fushi tarazu in Drosophila melanogaster results in ftz(Ual/Rpl)-like phenotypes and rescues ftz phenotypes.Semantic proximity Read ↗

The basis for a heat-induced developmental defect: defining crucial lesions.Semantic proximity Read ↗

Mutations affecting the stability of the fushi tarazu protein of Drosophila.Semantic proximity Read ↗

Generating loss-of-function phenotypes of the fushi tarazu gene with a targeted ribozyme in Drosophila.Semantic proximity Read ↗

How does the fushi tarazu gene activate engrailed in the Drosophila embryo?Semantic proximity Read ↗

Synthetic oligonucleotides recreate Drosophila fushi tarazu zebra-stripe expression.Semantic proximity Read ↗

Transcriptional regulation of the Drosophila homeotic gene teashirt by the homeodomain protein Fushi tarazu.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.