Article
The basis for a heat-induced developmental defect: defining crucial lesions.
Genes & development - 15 Sept 1995
Welte M A, Duncan I, Lindquist S
Abstract excerpt
Because lethal heat shocks perturb a multitude of cellular processes, the primary lesions responsible for death from heat stress remain to be defined. In Drosophila, sublethal heat treatments produce developmental anomalies that frequently mimic the effects of known mutations and are hence referred to as phenocopies. Mutations subject to phenocopy mimicry provide signposts to those biological processes most...
Topics
- Abdomen
- Animals
- Blastoderm
- Crosses, Genetic
- Culture Techniques
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Fushi Tarazu Transcription Factors
- Gene Expression Regulation, Developmental
- Heat-Shock Response