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Article

Vectors and parameters that enhance the efficacy of RNAi-mediated gene disruption in transgenic Drosophila.

Proceedings of the National Academy of Sciences of the United States of America - 22 Jun 2010

Haley Benjamin, Foys Bryon, Levine Michael

Abstract excerpt

Whole-genome transgenic RNAi libraries permit systematic genetic screens in individual tissues of Drosophila. However, there is a high incidence of nonspecific phenotypes because of off-target effects. To minimize such effects, it is essential to obtain a deeper understanding of the specificity o...

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Identifiers

PMID: 20534445
DOI: 10.1073/pnas.1006689107
PMCID: PMC2895090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20534445-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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