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Article

Association of the human papillomavirus type 16 E7 protein with the S-phase-specific E2F-cyclin A complex.

1 Oct 1993

Abstract excerpt

The transcription factor E2F has been shown to be involved in the expression of several cell cycle-regulated genes, and the activity of this factor is controlled by cellular proteins such as pRB and p107. E2F is also a target of the DNA virus oncoproteins (adenovirus E1A, simian virus 40 T antigen, and human papillomavirus [HPV] E7) (see the review by J. R. Nevins [Science 258: 424-429, 1992]). These viral...

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Identifiers

PMID: 8413252
DOI: 10.1128/mcb.13.10.6537

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Association of the human papillomavirus type 16 E7 protein with the S-phase-specific E2F-cyclin A complex.PMID 8413252Read ↗

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Induction of pRb Degradation by the Human Papillomavirus Type 16 E7 Protein Is Essential To Efficiently Overcome p16 <sup>INK4a</sup> -Imposed G <sub>1</sub> Cell Cycle ArrestSemantic proximity Read ↗

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Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteinsSemantic proximity Read ↗

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Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint.Semantic proximity Read ↗

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Analysis of the p53-mediated G1 growth arrest pathway in cells expressing the human papillomavirus type 16 E7 oncoproteinSemantic proximity Read ↗

The E7 proteins of the nononcogenic human papillomavirus type 6b (HPV-6b) and of the oncogenic HPV-16 differ in retinoblastoma protein binding and other propertiesSemantic proximity Read ↗

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