Article
Human papillomavirus type 16 E7 oncoprotein associates with E2F6.
Journal of virology - 1 Sept 2008
McLaughlin-Drubin Margaret E, Huh Kyung-Won, Münger Karl
Abstract excerpt
The papillomavirus life cycle is intimately coupled to the differentiation state of the infected epithelium. Since papillomaviruses lack most of the rate-limiting enzymes required for genome synthesis, they need to uncouple keratinocyte differentiation from cell cycle arrest and maintain or reestablish a replication-competent state within terminally differentiated keratinocytes. The human papillomavirus (HPV) E7...
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