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Article

Dbf2 is essential for cytokinesis and correct mitotic spindle formation in Candida albicans.

Molecular microbiology - 1 Jun 2009

González-Novo Alberto, Labrador Leticia, Pablo-Hernando M Evangelina, Correa-Bordes Jaime, Sánchez Miguel, Jiménez Javier, Vázquez de Aldana Carlos R

Abstract excerpt

We have characterized the DBF2 gene, encoding a protein kinase of the NDR family in Candida albicans, and demonstrate that this gene is essential for cell viability. Conditional mutants were constructed by using the MET3 promoter to analyse the phenotype of cells lacking this kinase. The absence of Dbf2 resulted in cells arrested as large-budded pairs that failed to contract the actomyosin ring, a function...

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Source

Identifiers

PMID: 19460099
DOI: 10.1111/j.1365-2958.2009.06729.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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