Article
Parental origin of mutant allele does not explain absence of gene dose in X-linked Hyp mice.
Genetical research - 1 Aug 1993
Qiu Z Q, Tenenhouse H S, Scriver C R
Abstract excerpt
The expectation for a gene dose effect in an X-linked phenotype is that the corresponding metrical trait in heterozygous females will lie between values for affected hemizygous males and unaffected males and females. We made sequential measurements (at 30, 60, 90, 120 and 150 days) of serum phosphate concentration and tail length in mice with X-linked hypophosphatemia (genotypes: Hyp/Y, Hyp/+ and Hyp/Hyp) and in...
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