Article
Femoral abnormalities and vitamin D metabolism in X-linked hypophosphatemic (Hyp and Gy) mice.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Jan 1995
Meyer R A, Meyer M H, Gray R W, Bruns M E
Abstract excerpt
X-linked hypophosphatemia is a genetic bone disease in humans and mice. Two closely linked mutations in mice, Hyp and Gy, cause low plasma phosphate and a rachitic and osteomalacic bone disease. Because of the controversy as to whether Gy is a good model for X-linked hypophosphatemia, the phenoty...
Topics
- Animals
- Bone Density
- Calcitriol
- Female
- Femur
- Genetic Linkage
- Hypophosphatemia, Familial
- Male
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Mutation