Article
par-2, a gene required for blastomere asymmetry in Caenorhabditis elegans, encodes zinc-finger and ATP-binding motifs.
Proceedings of the National Academy of Sciences of the United States of America - 21 Jun 1994
Levitan D J, Boyd L, Mello C C, Kemphues K J, Stinchcomb D T
Abstract excerpt
The par-2 gene of Caenorhabditis elegans functions in early embryogenesis to ensure an asymmetric first cleavage and the segregation of cytoplasmic factors. Both processes appear to be required to generate daughter blastomeres with distinct developmental potential. We isolated an allele of par-2...
Topics
- Adenosine Triphosphate
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Blastomeres
- Blotting, Northern
- Blotting, Southern
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Chromosomes, Artificial, Yeast
- Cloning, Molecular
- Consensus Sequence