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Article

Mutations can cause large changes in the conformation of a denatured protein.

Biochemistry - 5 Oct 1993

Flanagan J M, Kataoka M, Fujisawa T, Engelman D M

Abstract excerpt

Deletion of 13 amino acids from the carboxyl terminus of staphylococcal nuclease (WTSNase delta) results in a denatured, partially unfolded molecule that lacks significant persistent secondary structure but is relatively compact and monomeric under physiological conditions [Shortle & Meeker (1989) Biochemistry 28, 936-944; Flanagan et al. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 748-752]. Because of these and...

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PMID: 8399179
DOI: 10.1021/bi00090a011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Mutations can cause large changes in the conformation of a denatured protein.PMID 8399179Read ↗

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