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Article

The maturation of the immune response.

Immunology today - 1 Aug 1993

Berek C, Ziegner M

Abstract excerpt

In a T-cell dependent immune response, the repertoire of antigen-activated B cells is diversified by a hypermutation mechanism. Only high-affinity variants are selected into the pool of memory cells. This maturation process takes place in a special micro-environment, the germinal centre. Here, Cl...

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Identifiers

PMID: 8397779
DOI: 10.1016/0167-5699(93)90143-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8397779-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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