Inhibition of herpes simplex virus type 1 DNA replication by mutant forms of the origin-binding protein.

doi:10.1006/viro.1993.1496

Back to search

Article

Inhibition of herpes simplex virus type 1 DNA replication by mutant forms of the origin-binding protein.

Virology - 1 Oct 1993

Stow N D, Hammarsten O, Arbuckle M I, Elias P

Abstract excerpt

The herpes simplex virus type 1 (HSV-1) origin-binding protein (OBP) is a sequence-specific DNA binding protein encoded by gene UL9 which interacts with the viral origins of DNA replication and also exhibits DNA helicase activity. Sequence-specific DNA binding activity has previously been shown t...

Topics

Animals
Base Sequence
Cells, Cultured
Cricetinae
DNA Replication
DNA, Viral
DNA-Binding Proteins
Molecular Sequence Data
Mutation
Simplexvirus
Viral Proteins
Virulence

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.