Altered alpha 1-adrenoceptor binding in intact and adrenalectomized obese Zucker rats (fa/fa).

doi:10.1016/0006-8993(93)91028-q

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Article

Altered alpha 1-adrenoceptor binding in intact and adrenalectomized obese Zucker rats (fa/fa).

Brain research - 18 Jun 1993

Levin B E, Planas B, Routh V H, Hamilton J, Stern J S, Horwitz B A

Abstract excerpt

While many autonomic and metabolic defects associated with genetic obesity in the Zucker rat are corrected by adrenalectomy (Adx), brain adrenoceptor function has not been examined in this context. Here, 3 weeks after Adx or sham surgery, brains of 11 weeks old lean (Fa/Fa) and obese (fa/fa) male...

Topics

Adipose Tissue
Adrenalectomy
Animals
Autoradiography
Body Weight
Brain Chemistry
Genotype
Male
Obesity
Prazosin
Rats
Rats, Zucker
Receptors, Adrenergic, alpha

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