Article
Galanin in the hypothalamus of fed and fasted lean and obese Zucker rats.
Brain research - 24 Sept 1993
Beck B, Burlet A, Nicolas J P, Burlet C
Abstract excerpt
Galanin (GAL), a 29 aminoacid peptide, is widely distributed in the central nervous system and especially in the hypothalamus. It strongly stimulates food intake when it is injected in the paraventricular nucleus (PVN) of normal rats. The obese Zucker rat with a well-established hyperphagia is characterized by a general dysregulation of some important neuropeptides involved in the regulation of feeding behavior...
Topics
- Analysis of Variance
- Animals
- Arcuate Nucleus of Hypothalamus
- Body Weight
- Eating
- Energy Intake
- Fasting
- Galanin
- Genotype
- Hypothalamus
- Male
- Neuropeptide Y
