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Article

Specific increase in leptin production in obese (falfa) rat adipose cells.

The Biochemical journal - 15 Feb 2002

Turban Sophie, Hainault Isabelle, Truccolo Johan, Andre Jocelyne, Ferre Pascal, Quignard-Boulange Annie, Guerre-Millo Michèle

Abstract excerpt

In the obese state, enlarged adipose cells display an altered gene-expression profile and metabolic capacity. The aim of this study was to gain insight into their secretory function, by assessing two secreted proteins, leptin and angiotensinogen, in adipose cells of obese (fa/fa) Zucker rats. A marked and co-ordinate increase in leptin mRNA, gene transcription and promoter activity was observed in obese compared...

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Identifiers

PMID: 11829746
DOI: 10.1042/0264-6021:3620113
PMCID: PMC1222366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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