Article
Enhanced adrenergic excitation of serotonergic dorsal raphe neurons in genetically obese rats.
Neuroscience letters - 31 Oct 2002
Ohliger-Frerking Patricia, Horowitz John M, Horwitz Barbara A
Abstract excerpt
Serotonergic neurons in the dorsal raphe nucleus (DRN) project to the ventromedial hypothalamus (VMH), where serotonin (5-HT) release modulates feeding. 5-HT release in the VMH is altered in genetically obese vs. lean Zucker rats. Serotonergic DRN neurons are subject to adrenergic and serotonergic neuromodulation. To determine if the difference in 5-HT release between lean and obese rats might be due to...
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