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Article

Hypothalamic expression of urocortin 3 and the type 2 corticotropin-releasing factor receptor is regulated according to feeding state in lean but not obese Zucker rats.

Neuropharmacology - 1 Jul 2012

Poulin Anne-Marie, Lenglos Christophe, Mitra Arojit, Timofeeva Elena

Abstract excerpt

Urocortin 3 (Ucn3) is an anorexigenic neuropeptide with high affinity for the type 2 corticotropin-releasing factor receptor (CRF₂-R). How the expression of hypothalamic Ucn3 is regulated by fasting and refeeding in genetically obese (fa/fa) Zucker rats is not known. Obese Zucker rats develop early hyperphagia associated with low expression of CRF₂-R in the ventromedial hypothalamic nucleus (VMH) in this...

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PMID: 22227020
DOI: 10.1016/j.neuropharm.2011.12.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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