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Article

Serotonergic activity is depressed in the ventromedial hypothalamic nucleus of 12-day-old obese Zucker rats.

The American journal of physiology - 1 Sept 1994

Routh V H, Stern J S, Horwitz B A

Abstract excerpt

We previously reported lower ventromedial hypothalamic nucleus (VMN) serotonergic activity in 11-wk genetically obese vs. lean Zucker rats. To determine whether the activity was secondary to metabolic alterations associated with this established obesity (e.g., significant hyperphagia and hyperinsulinemia), we examined monoaminergic activity in various brain nuclei of 12-day lean (Fa/Fa and Fa/fa) and obese...

Topics

Adipose Tissue
Animals
Animals, Newborn
Body Weight
Dopamine
Genotype
Heterozygote
Homozygote
Hydroxyindoleacetic Acid
Hyperinsulinism
Insulin
Obesity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rats

Rats, Zucker

Reference Values

Serotonin

Ventromedial Hypothalamic Nucleus

Source

Identifiers

PMID: 7522410
DOI: 10.1152/ajpregu.1994.267.3.R712

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7522410-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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