Article
Cell phenotype-dependent control of Epstein-Barr virus latent membrane protein 1 gene regulatory sequences.
Virology - 1 Jul 1993
Fåhraeus R, Jansson A, Sjöblom A, Nilsson T, Klein G, Rymo L
Abstract excerpt
Growth transformation-associated Epstein-Barr virus-encoded genes are differentially regulated depending on the host cell phenotype. We have previously identified an LMP1 regulatory region (LRS) 5' of the LMP1 gene (+40 to -634) and analyzed its role in transcription initiation in the EBV-negative Burkitt's lymphoma line DG 75 (Fåhraeus et al., 1990a). In order to investigate the cell phenotype dependence of LMP1...
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