Article
Stimulation of NF-kappa B-mediated transcription by mutant derivatives of the latent membrane protein of Epstein-Barr virus.
Journal of virology - 1 May 1995
Mitchell T, Sugden B
Abstract excerpt
The latent membrane protein (LMP) of Epstein-Barr virus contributes to the immortalizing activity of the virus in primary, human B lymphocytes, but its mechanism of function is unknown. LMP is expressed at the plasma membrane and may act by influencing the signalling pathways of infected cells. L...
Topics
- 3T3 Cells
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Line
- DNA, Viral
- Genes, Reporter
- Herpesvirus 4, Human
- Humans
- Mice
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
- NF-kappa B
- Plasmids
- Transcription, Genetic
- Viral Matrix Proteins