Article
The constitution of a progesterone response element.
Molecular endocrinology (Baltimore, Md.) - 1 Apr 1993
Lieberman B A, Bona B J, Edwards D P, Nordeen S K
Abstract excerpt
Progesterone receptors (PRs) recognize and bind to DNA in a sequence-specific manner. To define the sequence-specific determinants of PR binding to DNA, we employed a detailed series of target elements and analyzed both PR binding in vitro and PR-mediated activation of a reporter gene in vivo. Th...
Topics
- Baculoviridae
- Base Composition
- Base Sequence
- Binding Sites
- Breast Neoplasms
- DNA
- DNA, Viral
- Gene Expression
- Humans
- Mammary Tumor Virus, Mouse
- Mifepristone
- Molecular Sequence Data
- Mutation
- Progestins
- Promegestone
- Receptors, Progesterone
- Transfection
- Tumor Cells, Cultured