Article
Definition of a negative modulation domain in the human progesterone receptor.
Molecular endocrinology (Baltimore, Md.) - 1 Sept 1998
Huse B, Verca S B, Matthey P, Rusconi S
Abstract excerpt
The progesterone receptor (PR) occurs in two major forms, the full-length PRB and the amino-truncated PRA, which lacks 164 amino-terminal residues. PRB functions as a strong transcriptional activator of progesterone-responsive genes, whereas PRA is inactive in several cell types where it may even...
Topics
- Amino Acid Sequence
- Animals
- Blotting, Western
- Chickens
- DNA
- HeLa Cells
- Humans
- Molecular Sequence Data
- Phenotype
- Progesterone
- Receptors, Progesterone
- Sequence Alignment
- Sequence Deletion
- Structure-Activity Relationship
- Transcriptional Activation
- Transfection