Article
Definition of a negative modulation domain in the human progesterone receptor.
Molecular endocrinology (Baltimore, Md.) - 1 Sept 1998
Huse B, Verca S B, Matthey P, Rusconi S
Abstract excerpt
The progesterone receptor (PR) occurs in two major forms, the full-length PRB and the amino-truncated PRA, which lacks 164 amino-terminal residues. PRB functions as a strong transcriptional activator of progesterone-responsive genes, whereas PRA is inactive in several cell types where it may even act as a trans-dominant repressor of PRB and other steroid receptors, like the glucocorticoid receptor or, reportedly,...
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