Article

A molecular toolbox to study progesterone receptor signaling

2023-07-20

Abstract excerpt

Progesterone receptor (PR) signaling is required for mammary gland development and homeostasis. A major bottleneck in studying PR signaling is the lack of sensitive assays to measure and visualize PR pathway activity both quantitatively and spatially. Here, we develop new tools to study PR signaling in human breast epithelial cells. First, we generate optimized Progesterone Responsive Element (PRE)-luciferase cons...

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Identifiers and source

Literature Corpus work: 57c48945-c81d-5eaf-85bf-baacfb88b636
DOI: 10.1101/2023.07.20.549847

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