Article
Specific binding of progesterone receptor to progesterone-responsive elements does not require prior dimerization.
European journal of biochemistry - 15 May 1993
Cohen-Solal K, Bailly A, Rauch C, Quesne M, Milgrom E
Abstract excerpt
Steroid-hormone receptors undergo, prior to binding to DNA, a hormone-dependent dimerization. It is generally accepted that this dimerization is indispensable for the high-affinity binding of hormone receptor to hormone-responsive elements. Using a progesterone-receptor mutant with the complete s...
Topics
- Animals
- Antibodies, Monoclonal
- Base Sequence
- Binding Sites
- Cell Line
- DNA, Viral
- Deoxyribonuclease I
- Electrophoresis, Polyacrylamide Gel
- Epitopes
- Mammary Tumor Virus, Mouse
- Mice
- Molecular Sequence Data