Article
Molecular diversity of precursor B acute lymphoblastic leukemias identified by the immunoglobulin heavy chain gene organization.
Leukemia - 1 Feb 1990
Nakamura K, Sasaki M, Fujimoto J, Enomoto Y, Kaneko Y, Ozaki M, Miyashita T, Tsunematsu Y, Hata J, Kobayashi N
Abstract excerpt
Acute leukemias with morphological, cytochemical, and immunological characteristics correlating to precursor B lymphocyte and with germ line configuration of immunoglobulin heavy (IgH) chain loci were studied for the organization of antigen receptor genes including C mu, Ig light (IgL) chain, T cell receptor (TCR) beta and gamma. Three of the five lymphoblast samples retained the germ line configuration of both...
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