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Article

Oncogene rearrangements in chronic B-cell leukemia.

Blood - 1 Apr 1991

Raghoebier S, van Krieken J H, Kluin-Nelemans J C, Gillis A, van Ommen G J, Ginsberg A M, Raffeld M, Kluin P M

Abstract excerpt

Forty-four B-chronic lymphocytic leukemias (CLL) were studied by Southern blot analysis using probes for the Ig genes and bcl-1, bcl-2 (major, minor and 5' breakpoint region), bcl-3, c-myc, and retinoblastoma (Rb) loci. Eight cases had three or more rearranged JH bands, indicating oligoclonality, clonal evolution, or chromosomal translocation. One case had a rearrangement of the bcl-1 locus and three of the bcl-2...

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PMID: 2009372

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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