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Article

Pathway correcting DNA replication errors in Saccharomyces cerevisiae.

The EMBO journal - 1 Apr 1993

Morrison A, Johnson A L, Johnston L H, Sugino A

Abstract excerpt

Mutation of predicted 3'-->5' exonuclease active site residues of Saccharomyces cerevisiae POL3 DNA polymerase (delta) or deletion of the PMS1 mismatch repair gene lead to relative (to wild type) spontaneous mutation rates of approximately 130 and 41, respectively, measured at a URA3 reporter gene inserted near to a defined replication origin. The POL3 exonuclease-deficient mutant pol3-01 generated most classes...

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Identifiers

PMID: 8385605
DOI: 10.1002/j.1460-2075.1993.tb05790.x
PMCID: PMC413358

Genes

PMS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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