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Article

Checkpoint-dependent activation of mutagenic repair in Saccharomyces cerevisiae pol3-01 mutants.

Molecular cell - 1 Sept 2000

Datta A, Schmeits J L, Amin N S, Lau P J, Myung K, Kolodner R D

Abstract excerpt

The Saccharomyces cerevisiae DNA polymerase delta proofreading exonuclease-defective mutation pol3-01 is known to cause high rates of accumulating mutations. The pol3-01 mutant was found to have abnormal cell cycle progression due to activation of the S phase checkpoint. Inactivation of the S phase checkpoint suppressed both the pol3-01 cell cycle progression defect and mutator phenotype, indicating that the...

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Identifiers

PMID: 11030339
DOI: 10.1016/s1097-2765(00)00058-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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