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Article

Quinolone action in Escherichia coli cells carrying gyrA and gyrB mutations.

FEMS microbiology letters - 15 Jan 1993

Herrera G, Aleixandra V, Urios A, Blanco M

Abstract excerpt

We have isolated spontaneous mutant strains of Escherichia coli KL16 showing different levels of nalidixic acid (NAL) resistance. From 40 independent mutants, 36 had gyrA and four had gyrB mutations. Most of the gyrA mutations (30/36) conferred high level NAL resistance. In contrast, the only gyrB mutation that conferred a relatively high level of NAL resistance also determined enhanced susceptibility to...

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Identifiers

PMID: 8384139
DOI: 10.1016/0378-1097(93)90079-h

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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