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Article

The invasive and metastatic properties of hormone-independent but hormone-responsive variants of MCF-7 human breast cancer cells.

Clinical & experimental metastasis - 1 Jan 1993

Thompson E W, Brünner N, Torri J, Johnson M D, Boulay V, Wright A, Lippman M E, Steeg P S, Clarke R

Abstract excerpt

We have previously isolated a series of MCF-7 human breast cancer cell variants which no longer require estrogen-supplementation for tumor growth in nude mice (Clarke et al. Proc Natl Acad Sci USA 86: 3649-3653, 1989). We now report that these hormone-independent and hormone-responsive variants (MIII, MCF7/LCC1) can invade locally from solid mammary fat pad tumors, and produce primary extensions on the surface of...

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Identifiers

PMID: 8380760
DOI: 10.1007/BF00880062

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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