Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The phenotypic and functional changes of rat Kupffer cells cultured with interleukin-2.

Toxicologic pathology - 1 Jan 1993

Inoue S, Yamashita A

Abstract excerpt

We examined the direct effects of human recombinant interleukin 2 (hrIL-2) in vitro on the phenotypic and the functional changes of rat Kupffer cells (KCs) isolated by collagenase perfusion and differential centrifugation. When KCs were cultured with high concentrations of hrIL-2, marked changes were dose-dependently observed in phenotypic expression, phagocytic activity, and accessory cell function compared to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cells, Cultured
Share to Interleukin-2
Share to Liver Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phagocytosis

Share to Phenotype

Share to Rats, Inbred Strains

Source

Identifiers

PMID: 8378708
DOI: 10.1177/019262339302100109

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The phenotypic and functional changes of rat Kupffer cells cultured with interleukin-2.PMID 8378708Read ↗

Development of a cytokine-producing immortalized murine Kupffer cell line.Semantic proximity Read ↗

M2-like Kupffer cells in fibrotic liver may protect against acute insult.Semantic proximity Read ↗

Phenotypic change and proliferation of murine Kupffer cells by colony-stimulating factors.Semantic proximity Read ↗

Characterization of two F4/80-positive Kupffer cell subsets by their function and phenotype in mice.Semantic proximity Read ↗

Altered Kupffer cell function in biliary obstruction.Semantic proximity Read ↗

Generation and functional characterization of a clonal murine periportal Kupffer cell line from H-2Kb -tsA58 mice.Semantic proximity Read ↗

Hepatocytes enhance effects of lipopolysaccharide on liver nonparenchymal cells through close cell interactions.Semantic proximity Read ↗

Liver injury model in mice induced by a cellular immunologic mechanism--delayed-type hypersensitivity-induced liver injury to picryl chloride and phenotype of effector cell.Semantic proximity Read ↗

Alterations in tumor necrosis factor-alpha expression by hepatic macrophages following acute cholestatic liver injury.Semantic proximity Read ↗

Interleukin-2-induced lymphoproliferative responses.Semantic proximity Read ↗

The nonopsonic allogeneic cell phagocytosis of macrophages detected by flow cytometry and two photon fluorescence microscope.Semantic proximity Read ↗

Lymphokine-activated killer (LAK) cells modulate the effects of IL-2 on a T cell-mediated immune response.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.