Article
The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion.
Molecular biology of the cell - 1 Mar 2009
Carvajal-Gonzalez Jose M, Mulero-Navarro Sonia, Roman Angel Carlos, Sauzeau Vincent, Merino Jaime M, Bustelo Xose R, Fernandez-Salguero Pedro M
Abstract excerpt
The dioxin receptor (AhR) modulates cell plasticity and migration, although the signaling involved remains unknown. Here, we report a mechanism that integrates AhR into these cytoskeleton-related functions. Immortalized and mouse embryonic fibroblasts lacking AhR (AhR-/-) had increased cell area...
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